牛磺鹅去氧胆酸-[D9]钠盐
牛磺鹅去氧胆酸钠(taurochenodeoxycholic acid sodium salt)
CAS: 6009-98-9
化学式: C26H44NNaO6S
| 中文名 | 牛磺鹅去氧胆酸钠 |
| 英文名 | taurochenodeoxycholic acid sodium salt |
| 别名 | 牛磺去氧鹅胆酸钠 牛磺鹅脱氧胆酸钠 牛磺鹅去氧胆酸钠 牛磺鹅脱氧胆酸钠盐 熊去氧胆酸杂质15 牛磺鹅去氧胆酸-[D4]钠盐 牛磺鹅去氧胆酸-[D9]钠盐 牛磺鹅去氧胆酸钠(TCDCA) |
| 英文别名 | Sodium taurochenodeoxycholate taurochenodeoxycholic acid soduim salt taurochenodeoxycholic acid sodium salt Taurochenodeoxycholic Acid, Sodium Salt Taurochenodeoxycholic Acid D4 Sodium Salt sodium 2-[(3,7-dihydroxy-24-oxocholan-24-yl)amino]ethanesulfonate 5BETA-CHOLANIC ACID-3ALPHA,7ALPHA-DIOL-24-N-(2-SULFOETHYL)-AMIDE SODIUM 3α,7α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt 5-BETA-CHOLANIC ACID-3-ALPHA, 7-ALPHA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT 2-([3-ALPHA,7-ALPHA-DIHYDROXY-24-OXO-5-BETA-CHOLAN-24-YL]AMINO)ETHANESULFONIC ACID 2-[(3ALPHA,7ALPHA-DIHYDROXY-24-OXO-5BETA-CHOLAN-24-YL)AMINO]ETHANESULFONIC ACID SODIUM SALT ethanesulfonic acid, 2-[[(3alpha,5beta,7alpha)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-, monosodium salt Sodium taurochenodeoxycholate,2-([3α,7α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid sodium salt, 3α,7α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt, Taurochenodeoxy |
| CAS | 6009-98-9 |
| 化学式 | C26H44NNaO6S |
| 分子量 | 521.69 |
| InChI | InChI=1/C26H45NO6S.Na/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29;/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/t16-,17+,18-,19-,20+,21+,22-,24+,25+,26-;/m1./s1 |
| 熔点 | 165-175 °C |
| 沸点 | 215 °C(lit.) |
| 溶解度 | 甲醇 (微溶) 、水 (微溶) |
| 存储条件 | room temp |
| 稳定性 | 吸湿性 |
| 敏感性 | Easily absorbing moisture |
| 外观 | 固体 |
| 颜色 | White to Off-White |
| BRN | 3901205 |
| MDL号 | MFCD00036745 |
| 体外研究 | Taurochenodeoxycholic acid dramatically improves the apoptosis rate of NR8383 cells in a concentration-dependent manner. In the meantime, Taurochenodeoxycholic acid significantly augments PKC mRNA levels, activities and increases JNK, caspase-3 and caspase-8 mRNA expression levels, activities. |
| 体内研究 | Taurochenodeoxycholic acid (0.05, 0.1g/kg) decreases the pulmonary coefficient in the model mice and reduces the pathological damages on their lungs; it can decrease the expression levels of TNF-α and TIMP-2 in pulmonary tissues in the pulmonary fibrosis mice and has no significant effects on MMP2. Taurochenodeoxycholic acid significantly normalizes the clinical inflammatory parameters, prevented indomethacin-induced increases in the biliary contents of secondary bile acids and hydrophobicity index, and tended to attenuate the intestinal inflammation. Taurochenodeoxycholic acid significantly suppresses paw swelling and polyarthritis index, increases the loss body weight and index of thymus and spleen, and amends radiologic changes in AA rats. The overproduction and mRNA expression of TNF-α, IL-1β and IL-6 are remarkably suppressed in serum and synovium tissue of all TCDCA-treated rats. |
| 安全术语 | 24/25 - 避免与皮肤和眼睛接触。 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10 |
| 海关编号 | 29309090 |
![牛磺鹅去氧胆酸-[D9]钠盐](http://res.chembk.com/assets/str/2d/6/60/6009-98-9.png)
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现货供应
产品名: 牛磺鹅去氧胆酸钠；牛磺鹅脱氧胆酸钠 询盘CAS: 6009-98-9
产地: 广东
包装: 100克、500克、1000克
规格: 工业级 含量99% 白色结晶或粉末
价格: 电联
库存: 现货
电话: 19849939632
手机: 19849939632(微信同号）
电子邮件: 2470479589@qq.com
QQ: 2470479589
微信: +86 19849939632
产品描述: 中文名称牛磺鹅去氧胆酸钠 中文同义词牛磺去氧鹅胆酸钠;熊去氧胆酸杂质15;牛磺鹅脱氧胆酸钠;牛磺鹅去氧胆酸钠(TCDCA);牛磺鹅去氧胆酸钠;牛磺鹅脱氧胆酸钠 更多
现货供应
产品名: 牛磺鹅去氧胆酸钠；牛磺鹅脱氧胆酸钠 询盘CAS: 6009-98-9
产地: 广东
包装: 100克、500克、1000克
规格: 工业级 含量99% 白色结晶或粉末
价格: 电联
库存: 现货
电话: 19849939632
手机: 19849939632(微信同号）
电子邮件: 2470479589@qq.com
QQ: 2470479589
微信: +86 19849939632
产品描述: 中文名称牛磺鹅去氧胆酸钠 中文同义词牛磺去氧鹅胆酸钠;熊去氧胆酸杂质15;牛磺鹅脱氧胆酸钠;牛磺鹅去氧胆酸钠(TCDCA);牛磺鹅去氧胆酸钠;牛磺鹅脱氧胆酸钠 更多
牛磺鹅去氧胆酸-[D9]钠盐的上游原料
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